KMID : 1103720120670050387
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Journal of the Korean Society of Radiology 2012 Volume.67 No. 5 p.387 ~ p.395
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Follow-Up of Cryoablated Renal Cell Carcinoma with Residual Contrast Enhancement on CT and MRI
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Park Eun-Kyung
Sung Deuk-Jae Park Beon- Jin Kim Min-Ju Han Na-Yeon Cho Sung-Bum Kang Seok-Ho
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Abstract
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Purpose: To describe the characteristics of residual contrast enhancement (CE) in cryoablated renal cell carcinoma (RCC) with regard to eventual resolution and the presence of residual tumor on follow-up CT and MRI.
Materials and Methods: 22 patients with 24 RCCs underwent laparoscopic renal cryoablation and follow-up CT (n = 19) and MRI (n = 3) for a mean of 28 months. Two radiologists retrospectively assessed the CT and MRI images for the tumor size and characteristics of residual CE in the cryolesions: peripheral rim (< 10% of the maximum cryolesion diameter), focal eccentric (10-25%), and thick internal enhancement (> 25%).
Results: Residual CE was seen in 13 cryolesions (54%) at 3-month follow-up. Peripheral rim and focal eccentric enhancement was seen in six (25%) and four (16.7%) cryolesions, persisted for a mean follow-up of 4.5 and 6 months, and disappeared completely at a mean follow-up of 10.5 and 12 months, respectively. Three (12.5%) cryolesions showed persistent thick internal enhancement at 6-month follow-up, and were treated with radiofrequency ablation or chemotherapy. The cryolesions had decreased in size by an average of 20.2% and 39.7% at 6 and 12 months after cryoablation, respectively.
Conclusion: Follow-up for ¡Ã 12 months is needed to assess treatment outcomes in patients with peripheral rim or focal eccentric enhancement of cryoablated RCCs, which may persist until 12 months postoperatively without remnant viable tumor.
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KEYWORD
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Renal Cell Carcinoma, Cryoablation, Postablation Imaging
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